Date: 2022-02-24 06:29 pm (UTC)
itmeanscourage: (shocked)
From: [personal profile] itmeanscourage
Isamu nodded. It was a very thoughtful interpretation of the two of them joined together. He could appreciate that.

“It… would mean nothing? I do not under…” His voice trailed off, various comments from multiple individuals on what was socially acceptable in this particular world. “Is it because such things are frowned upon here? Or are there differences between your countries of origin?”

Mick and Ziggy were definitely getting married. Right?

Date: 2022-02-25 12:38 pm (UTC)
itmeanscourage: (shocked)
From: [personal profile] itmeanscourage
Isamu pursed his lips, silent for a few moments. In his world, that was not the case. While there still some countries that followed older religious or tribal traditions, the vast majority of the world’s powers had long since retreated from the ridiculous notion of legislating who one could love. He’d grown up in a world where the gay rights movement, like women’s rights and the civil rights movement, all happened before he was even born. (Before his parents were even born, technically.)

“That certainly complicates things.” He eventually replied. “How are Mick and Ziggy solving for this outdated legal lunacy? Could you not do something similar?”

Because while Ziggy was an Anthean female, on this world, he was officially considered male. So wouldn’t that couple be in the exact same boat as Rekker?

Date: 2022-02-28 05:56 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
“Hmmm…” Isamu hummed thoughtfully. Those kind of legal ramifications did make the situation infinitely more complicated.

Mick’s relationship with Ziggy was an entirely different kind of complicated. After all, if Ziggy were hospitalized, visitation rights and access to medical records would pale in comparison to the larger issue of him being a literal alien. Antheans might not even have a concept of a last will and testament. Isamu didn’t know.

There was also a lot about this world that Isamu did not know.

“Are there countries in this world where such a partnership is, without a doubt, legally recognized? How difficult would it be to set up residency in a new nation, or even obtain citizenship there?”

Date: 2022-03-06 05:53 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
Isamu hummed as he nodded. Rekker had done considerable research into the topic, which was not surprising. What was surprising, however, were the results - but that boiled down to a lot of differences between their worlds.

Where Isamu came from, same sex marriage had been legal in his country for decades. And the path to citizenship was closer to a three to five year process, depending on the situation. He remembered doing research on the topic back when he and his brother turned 22. Because their parents maintained their Japanese citizenry (and only lawful permanent residency in the United States), they had to technically abide by Japanese law to either choose their nationality or retroactively lose it. It was far simpler to check the box on the latter, so to speak, so they both sent their letters and declared their intent to remain U.S. citizens.

“Citizenship laws are complicated…” he commiserated. “And unfortunately, Mama and Papa were already married when they applied for visas to study in America. And they both received independent employer sponsorship, Papa as a biomedical engineer and Mama as a clinical engineer. So even if we were in the same world, the situations are rather different.”

Rekker was in quite a pickle.

He couldn’t even suggest the Nexus. While they could undoubtedly get married there, interdimensional law (if such a field even existed) was definitely not his forte.

Date: 2022-03-06 08:44 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
“Actually, if you are unable to abide by an unjust law, working to actively change that laws could be a worthwhile endeavor. There may be loopholes too, that a lawyer may know and the layperson may be unaware of.”

Honestly, given the chaos that Tom vented about on the regular, and the things he and Ziggy had to hide at all costs, the lawyers they kept on retainer had to be some of the best in the world. If anyone could help on that front, they probably could.

Date: 2022-03-10 12:57 pm (UTC)
itmeanscourage: (shocked)
From: [personal profile] itmeanscourage
“I confess, this is now quite far from my area of expertise.”

Breakfast was as good as done or long forgotten by this point. Isamu was fairly certain that anything he said would rile Rekker up even more. The emotions were entirely justified, given the blatant injustice of the situation, but it still made Isamu wary.

Date: 2022-03-10 06:37 pm (UTC)
itmeanscourage: (inquisitive)
From: [personal profile] itmeanscourage
The awkward silence gave Isamu enough time check on the data simulations he was running and then begin another set.

“Biochemistry.” He replied. “With a slight specialization in neurochemistry.”

Though he had worked on a variety of research projects with his fellow IRIS researchers, some not even in his chosen field. Working with Dr. Malcom on a survey of mass extinction events was fascinating.

“I am currently doing a significant amount of research into brainwave patterns and neurotransmitter levels associated with altered states of consciousness.”

Date: 2022-03-12 02:50 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
“Whether or not your brain would fuck up my work, as you put it, would be entirely dependent on what I was intending to measure.”

Despite the delicate subject matter, once the topic of conversation turned scientific, Isamu was mentally sorting through the veritable catalog of information he had read on the neurobiology of depressive disorders, the multi-faceted developmental and signalling actions of serotonin in regulating depressive symptoms, and even the glutamate-driven alterations in synaptic connectivity within the pre-frontal cortex. He nodded as Rekker spoke,

“Was the study successfully peer-reviewed and published?” He eventually asked. “I would like to read it.”

Date: 2022-03-14 05:58 pm (UTC)
itmeanscourage: (Default)
From: [personal profile] itmeanscourage
Isamu nodded. “Yes, I do recall a few studies comparing structural differences in that region of the brain with deficient cognitive control and impaired decision-making in the context of intense emotions. And a few following similar changes in the ventrolateral prefrontal cortex and dorsal prefrontal cortex.”

Of course, there were other studies on other parts of the brain - the amygdala, the anterior cingulate cortex, the pons, for example - that also played a role in impulsive behaviors, heightened stress reactions, difficulty regulating emotions or perceiving pain. Honestly, finding a true biosignature for suicidal thoughts and major depressive disorder was still a massive challenge. The same findings weren’t always detected across multiple studies.

“Some of these differences seem to be be more pronounced among those who employed violent methods in their suicide attempt, though there are enough conflicting findings that many individuals with suicidal thoughts and behaviors may not exhibit consistent structural differences at all.” He mused aloud.

Date: 2022-03-14 08:33 pm (UTC)
itmeanscourage: (Default)
From: [personal profile] itmeanscourage
Isamu was startled at first by the frank first-hand description of such behavior, but remained stoic. This was still a scientific discussion after all. And he found himself glancing at the place setting, even though the server had taken away both their plates and silverware by this point.

“Those aforementioned structural abnormalities, hyperactivity in certain portions of the hippocampus and amygdala, and potential underactivation of thalamic areas involved in pain, would be quite the combination.” He agreed, though not with a tone that would suggest he thought Rekker was broken. “Quite the case study.”

Date: 2022-03-14 11:07 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
“I do not mean to suggest that you do not feel it. I should have specified that I was not referring merely to the sensory processing of pain intensity. There is compelling evidence to suggest the affective processing of pain - its unpleasantness - may be different in individuals who participate in self-harming behaviors.” He corrected himself. “Not to mention the fact that pain is modulated by contextual stimuli, such as emotions, social factors or other perceptions.”

And that didn’t even begin to analyze the potential role of abnormal feedback in the striatal dopamine system, or dysfunctions of the hypothalamic-pituitary-adrenal axis and its altered secretion of stress hormones and affect on serotonin.

Date: 2022-03-15 12:03 pm (UTC)
itmeanscourage: (Default)
From: [personal profile] itmeanscourage
“I dare say wires being crossed is quite an appropriate metaphor, as fMRI studies have documented masochists activating brain areas involved in sensory processing rather than affective pain processing when they receive painful stimuli within that particular context.” He nodded. “But through involvement of the parietal operculum, which suggests additional cognitive evaluation, not the ventral striatum, which would suggest the processing of rewards.”

In other words, it was less about pleasure and more about memory and cognitive reevaluation. Which seemed to fit with Rekker’s desire to remain in control of his pain. At least partially.

Date: 2022-03-17 12:01 pm (UTC)
itmeanscourage: (thoughtful)
From: [personal profile] itmeanscourage
That revelation made Isamu pause.

“Hmm… That runs counter to what a number of studies have found, but that does not mean it cannot be ruled out. After all, opioid and dopaminergic systems and the HPA axis can both be activated either by psychoactive drugs or by behaviors. So it is still plausible that for a subset of cases, the same biological mechanisms support the development of addiction as well as self-harming behaviors.”

Comorbidity at its finest. Wires getting crossed.

(no subject)

From: [personal profile] itmeanscourage - Date: 2022-03-19 01:31 am (UTC) - Expand

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Derek "Rekker" Sterling

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