“I dare say wires being crossed is quite an appropriate metaphor, as fMRI studies have documented masochists activating brain areas involved in sensory processing rather than affective pain processing when they receive painful stimuli within that particular context.” He nodded. “But through involvement of the parietal operculum, which suggests additional cognitive evaluation, not the ventral striatum, which would suggest the processing of rewards.”
In other words, it was less about pleasure and more about memory and cognitive reevaluation. Which seemed to fit with Rekker’s desire to remain in control of his pain. At least partially.
"I don't understand all of that." Isamu had forged past Rekker's understanding of the medical terminology about his condition. While being curious he wasn't a scientist, though he did understand many of the scientific terms when it came to mental health.
"I know it feels like an addict getting a hit after being off for a long time." He could speak to that having both had a time of wrestling with drugs and alcohol. "I don't always realize how much I've done until I come out the other side. Things can trigger it starting too, like when a cokehead sees cocaine and can't resist. Sharp objects can trigger me the same way, especially if I'm already down."
“Hmm… That runs counter to what a number of studies have found, but that does not mean it cannot be ruled out. After all, opioid and dopaminergic systems and the HPA axis can both be activated either by psychoactive drugs or by behaviors. So it is still plausible that for a subset of cases, the same biological mechanisms support the development of addiction as well as self-harming behaviors.”
Rekker gave a non committal shrug. "I'm speaking as someone who was an addict and is still suicidal. Studies are only as good as the questions they ask."
Rekker had been in enough studies by this point but still stifled a laugh. "I don't just like pain when I'm trying to off myself or feel like shit."
He left the implications of what he was talking about unsaid for now, unless the twin asked.
Isamu’s eyes widened for a moment, though he felt no need to ask for clarification. He could easily read between the lines, and scoffed a hasty, “whatever releases dopamine in your nucleus accumbens, I suppose…”
That sort of thing was not a turn-on for the scientist. And unfortunately, very little scientific literature actually existed on that particular subject to fill in the gaps.
Rekker just shrugs and laughs at the reaction because what else can you really do? It takes all kinds of people and relationships were built on the right kind of strange coming together.
"When you're angry and depressed healthy outlets are important." Which was a more scientific approach to the shocking unspoken. "How's the number crunching going?"
It was time to change the subject even if he was amused and would, if it were one of the band, continue to harass.
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rage_rekker) wrote2021-08-11 04:17 am
no subject
In other words, it was less about pleasure and more about memory and cognitive reevaluation. Which seemed to fit with Rekker’s desire to remain in control of his pain. At least partially.
no subject
"I know it feels like an addict getting a hit after being off for a long time." He could speak to that having both had a time of wrestling with drugs and alcohol. "I don't always realize how much I've done until I come out the other side. Things can trigger it starting too, like when a cokehead sees cocaine and can't resist. Sharp objects can trigger me the same way, especially if I'm already down."
no subject
“Hmm… That runs counter to what a number of studies have found, but that does not mean it cannot be ruled out. After all, opioid and dopaminergic systems and the HPA axis can both be activated either by psychoactive drugs or by behaviors. So it is still plausible that for a subset of cases, the same biological mechanisms support the development of addiction as well as self-harming behaviors.”
Comorbidity at its finest. Wires getting crossed.
no subject
Rekker had been in enough studies by this point but still stifled a laugh. "I don't just like pain when I'm trying to off myself or feel like shit."
He left the implications of what he was talking about unsaid for now, unless the twin asked.
no subject
That sort of thing was not a turn-on for the scientist. And unfortunately, very little scientific literature actually existed on that particular subject to fill in the gaps.
no subject
"When you're angry and depressed healthy outlets are important." Which was a more scientific approach to the shocking unspoken. "How's the number crunching going?"
It was time to change the subject even if he was amused and would, if it were one of the band, continue to harass.