Isamu nodded. “Yes, I do recall a few studies comparing structural differences in that region of the brain with deficient cognitive control and impaired decision-making in the context of intense emotions. And a few following similar changes in the ventrolateral prefrontal cortex and dorsal prefrontal cortex.”
Of course, there were other studies on other parts of the brain - the amygdala, the anterior cingulate cortex, the pons, for example - that also played a role in impulsive behaviors, heightened stress reactions, difficulty regulating emotions or perceiving pain. Honestly, finding a true biosignature for suicidal thoughts and major depressive disorder was still a massive challenge. The same findings weren’t always detected across multiple studies.
“Some of these differences seem to be be more pronounced among those who employed violent methods in their suicide attempt, though there are enough conflicting findings that many individuals with suicidal thoughts and behaviors may not exhibit consistent structural differences at all.” He mused aloud.
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Date: 2022-03-14 05:58 pm (UTC)Of course, there were other studies on other parts of the brain - the amygdala, the anterior cingulate cortex, the pons, for example - that also played a role in impulsive behaviors, heightened stress reactions, difficulty regulating emotions or perceiving pain. Honestly, finding a true biosignature for suicidal thoughts and major depressive disorder was still a massive challenge. The same findings weren’t always detected across multiple studies.
“Some of these differences seem to be be more pronounced among those who employed violent methods in their suicide attempt, though there are enough conflicting findings that many individuals with suicidal thoughts and behaviors may not exhibit consistent structural differences at all.” He mused aloud.